Thursday, February 28, 2013

Gut microbiota research: Pinpointing a moving target

Gut microbiota research: Pinpointing a moving target [ Back to EurekAlert! ] Public release date: 27-Feb-2013
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Contact: Aimee Frank
afrank@gastro.org
301-941-2620
American Gastroenterological Association

(27 February 2013) Although considerable progress has been made in determining the impact of the gut microbiota on the development of inflammatory bowel disease (IBD) and other gastrointestinal (GI) diseases, the detailed study and understanding of the composition and effects of this intestinal community still faces numerous methodological and empirical challenges.

"Improvement of study design and sample collection, as well as a more precise understanding of the various genetic and environmental influences, are asked for," says Professor Dirk Haller (Technical University Munich, Germany), who addressed some of the central issues that make up the agenda of future research. Further information on this issue one of many topics presented at the 2nd World Summit "Gut Microbiota For Health" in Madrid, Spain, from 24 to 26 February 2013 can be found at http://bit.ly/WED27PR.

To keep themselves up to date on the rapidly increasing advances in the field of gut microbiota research, scientists and health-care professionals came together at the 2nd Gut Microbiota For Health World Summit. This year, the event was hosted by the Gut Microbiota & Health Section of the European Society of Neurogastroenterology and Motility (ESNM) a member of United European Gastroenterology (UEG) and the American Gastroenterological Association (AGA), with the support of Danone Dairy.

A recent overview of gut microbiota research titled "Gut microbiota and gastrointestinal health: current concepts and future directions" has been published in Neurogastroenterology and Motility (Volume 25, Issue 1, pages 415, January 2013), the official journal of the ESNM and the American Neurogastroenterology and Motility Society (ANMS). The article is the first publication of ESNM's Gut Microbiota & Health Section and can be downloaded at http://onlinelibrary.wiley.com/doi/10.1111/nmo.12046/full.

###

About the Gut Microbiota For Health Experts Exchange website

The www.gutmicrobiotaforhealth.com Experts Exchange, provided by the Gut Microbiota & Health Section of ESNM, is an online platform for health-care professionals, scientists, and other people interested in the field. Thanks to being an open, independent and participatory medium, this digital service enables a scientific debate in the field of gut microbiota.

Connected to www.gutmicrobiotaforhealth.com, the Twitter account @GMFHx, animated by experts, for experts from the medical and scientific community, actively contributes to the online exchanges about the gut microbiota. Follow @GMFHx on Twitter. You can follow the Twitter coverage of the event using #GMFH2013.

About the Gut Microbiota & Health Section of ESNM

ESNM stands for the European Society of Neurogastroenterology and Motility, a member of United European Gastroenterology (UEG). The mission of the ESNM is to defend the interests of all professionals in Europe involved in the study of neurobiology and pathophysiology of gastrointestinal function. The Gut Microbiota & Health Section was set up to increase recognition of the links between the gut microbiota and human health, to spread knowledge and to raise interest in the subject. The Gut Microbiota & Health Section is open to professionals, researchers, and practitioners from all fields related to gut microbiota and health. www.esnm.eu/gut_health/gut_micro_health.php?navId=68

About the AGA

The American Gastroenterological Association is the trusted voice of the GI community. Founded in 1897, the AGA has grown to include more than 16,000 members from around the globe who are involved in all aspects of the science, practice and advancement of gastroenterology. The AGA Institute administers the practice, research and educational programmes of the organisation. www.gastro.org

About Danone Dairy and Gut Microbiota For Health

Danone's conviction is that food plays an essential role in human health namely through the impact that gut microbiota may have on health. That is why Danone Dairy supports the Gut Microbiota For Health World Summit and Experts Exchange web platform with the aim to encourage research and increase knowledge in this promising area, in line with its mission to "bring health through food to as many people as possible."


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Gut microbiota research: Pinpointing a moving target [ Back to EurekAlert! ] Public release date: 27-Feb-2013
[ | E-mail | Share Share ]

Contact: Aimee Frank
afrank@gastro.org
301-941-2620
American Gastroenterological Association

(27 February 2013) Although considerable progress has been made in determining the impact of the gut microbiota on the development of inflammatory bowel disease (IBD) and other gastrointestinal (GI) diseases, the detailed study and understanding of the composition and effects of this intestinal community still faces numerous methodological and empirical challenges.

"Improvement of study design and sample collection, as well as a more precise understanding of the various genetic and environmental influences, are asked for," says Professor Dirk Haller (Technical University Munich, Germany), who addressed some of the central issues that make up the agenda of future research. Further information on this issue one of many topics presented at the 2nd World Summit "Gut Microbiota For Health" in Madrid, Spain, from 24 to 26 February 2013 can be found at http://bit.ly/WED27PR.

To keep themselves up to date on the rapidly increasing advances in the field of gut microbiota research, scientists and health-care professionals came together at the 2nd Gut Microbiota For Health World Summit. This year, the event was hosted by the Gut Microbiota & Health Section of the European Society of Neurogastroenterology and Motility (ESNM) a member of United European Gastroenterology (UEG) and the American Gastroenterological Association (AGA), with the support of Danone Dairy.

A recent overview of gut microbiota research titled "Gut microbiota and gastrointestinal health: current concepts and future directions" has been published in Neurogastroenterology and Motility (Volume 25, Issue 1, pages 415, January 2013), the official journal of the ESNM and the American Neurogastroenterology and Motility Society (ANMS). The article is the first publication of ESNM's Gut Microbiota & Health Section and can be downloaded at http://onlinelibrary.wiley.com/doi/10.1111/nmo.12046/full.

###

About the Gut Microbiota For Health Experts Exchange website

The www.gutmicrobiotaforhealth.com Experts Exchange, provided by the Gut Microbiota & Health Section of ESNM, is an online platform for health-care professionals, scientists, and other people interested in the field. Thanks to being an open, independent and participatory medium, this digital service enables a scientific debate in the field of gut microbiota.

Connected to www.gutmicrobiotaforhealth.com, the Twitter account @GMFHx, animated by experts, for experts from the medical and scientific community, actively contributes to the online exchanges about the gut microbiota. Follow @GMFHx on Twitter. You can follow the Twitter coverage of the event using #GMFH2013.

About the Gut Microbiota & Health Section of ESNM

ESNM stands for the European Society of Neurogastroenterology and Motility, a member of United European Gastroenterology (UEG). The mission of the ESNM is to defend the interests of all professionals in Europe involved in the study of neurobiology and pathophysiology of gastrointestinal function. The Gut Microbiota & Health Section was set up to increase recognition of the links between the gut microbiota and human health, to spread knowledge and to raise interest in the subject. The Gut Microbiota & Health Section is open to professionals, researchers, and practitioners from all fields related to gut microbiota and health. www.esnm.eu/gut_health/gut_micro_health.php?navId=68

About the AGA

The American Gastroenterological Association is the trusted voice of the GI community. Founded in 1897, the AGA has grown to include more than 16,000 members from around the globe who are involved in all aspects of the science, practice and advancement of gastroenterology. The AGA Institute administers the practice, research and educational programmes of the organisation. www.gastro.org

About Danone Dairy and Gut Microbiota For Health

Danone's conviction is that food plays an essential role in human health namely through the impact that gut microbiota may have on health. That is why Danone Dairy supports the Gut Microbiota For Health World Summit and Experts Exchange web platform with the aim to encourage research and increase knowledge in this promising area, in line with its mission to "bring health through food to as many people as possible."


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-02/aga-gmr022713.php

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Jordan sees new surge in Syrians fleeing civil war

AMMAN, Jordan (AP) ? A Jordanian official says there is a new surge in Syrians fleeing across the border to Jordan as fighting intensifies in southern Syria.

A government spokesman for Syrian refugee affairs told The Associated Press on Wednesday that Jordan now hosts 418,529 Syrian refugees.

Anmar Hmoud says 2,490 Syrians crossed into Jordan overnight, with the numbers averaging about 3,000 per night in recent days.

By the end of March, Jordan could have as many as half a million Syrian refugees.

Some of those coming through unofficial border crossings find shelter in Jordan's Zaatari camp, now home to more than 105,700 refugees. Many more live among Jordanian families.

The camp has seen sporadic violent protests over its harsh desert conditions.

The U.N. says there are nearly 925,000 Syrians displaced throughout the region.

Source: http://news.yahoo.com/jordan-sees-surge-syrians-fleeing-civil-war-091349477.html

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Optical materials: Light's magnetism shows its true colors

Feb. 27, 2013 ? Light is an oscillating wave of electric and magnetic fields. The way the electric field component interplays with the atoms in a material largely determines how light interacts with matter. With visible light, however, the influence of the magnetic component is usually much smaller. Arseniy Kuznetsov at the A*STAR Data Storage Institute, Singapore, and co?workers have now created tiny spheres of silicon that can strongly interact with the magnetic field of visible-wavelength light1. These engineered 'magnetic materials' enable new ways of controlling light at the nanoscale.

Relative permeability is a measure of a substance's ability to support a magnetic field. Most optical materials have a permeability approximately equal to one. A more diverse choice, however, would open the door to a whole host of novel optical devices. Negative permeability, for example, could be used to create high-resolution lenses and even invisibility cloaks. As no such materials exist in nature, scientists have started to develop metamaterials, which are artificial structures engineered to interact with light in a desired way. Kuznetsov and co-workers have shown that nanoscale engineering provides a way of tuning the magnetic properties of silicon nanoparticles.

The researchers fired a high-intensity laser at a silicon wafer, which blasted off spheres of silicon with diameters between 100 and 200 nanometers. The separation between the spheres was large enough that the researchers could see them individually under an optical microscope. They could also see that the nanoparticles scattered light of all colors in the rainbow, from red to violet.

In a theoretical analysis, Kuznetsov and co-workers showed that the optical response resulted from incoming light generating a circular electric field, or displacement current, in the sphere. This, in turn, supported an oscillating magnetic field in the middle of the particle -- a so-called magnetic dipole (see image). "We have experimentally demonstrated that silicon nanoparticles can have strong electric and magnetic dipole resonances in the visible spectrum," explains Kuznetsov. "The advantage of our approach is that it is free of energy loss because the modes are not related to real electron currents."

The properties of the dipole were dependent on the size of the particle, so particles of different sizes scattered light of different colors. The team predicts that more sophisticated fabrication techniques will soon enable greater control over a nanoparticle's size and shape, thus enabling selective tuning of its optical properties. "Our future research will target possible applications of these nanoparticles and the realization of novel nanodevices for light-on-a-chip integration," says Kuznetsov.

The A*STAR-affiliated researchers contributing to this research are from the Data Storage Institute.

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Story Source:

The above story is reprinted from materials provided by The Agency for Science, Technology and Research (A*STAR).

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Arseniy I. Kuznetsov, Andrey E. Miroshnichenko, Yuan Hsing Fu, JingBo Zhang, Boris Luk?yanchuk. Magnetic light. Scientific Reports, 2012; 2 DOI: 10.1038/srep00492

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/matter_energy/electricity/~3/Y9MFsXJiOsQ/130227124657.htm

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Cynaps Bluetooth Bone Conduction Headset review

You may be wondering why I am showing a picture of a Nike Dri-Fit baseball hat as my intro image for this review. I agree most hats are not very high tech or gadgety. But in this case, looks can be deceiving. While this review is in some minor part about the hat you see, [...]

Source: http://the-gadgeteer.com/2013/02/27/cynaps-bluetooth-bone-conduction-headset-review/

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Wednesday, February 27, 2013

Whats in the Box? *Mature* 02/25 by One Gaming Community | Blog ...

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    On his show, Comedian Rodney Perry covers arts and entertainment, everything from comedy and politics to music and acting, with his signature comedic slant.

  • MashUp Radio is a 30-minute podcast that discusses the fusion of technology, life, culture and science. Host Peter Biddle, engineer and executive for Intel?s Atom Software, dishes up a thought-provoking discussion.

  • Joy Keys provides her listeners with insight to improve their lives mentally, physically, monetarily and emotionally. Past guests on the show have included Meshell Nedegeocello, Blair Underwood, in addition to an impressive list of CEOs, humanitarians and authors.

  • Host Barry Moltz gets small businesses unstuck. He has founded and run small businesses with a great deal of success and failure for more than 15 years. This is a business radio show where he shares all the craziness of small business. It?s that craziness that actually makes it exciting, interesting and totally unpredictable.

  • The Bottom Line Sports Show is hosted by former NBA stars Penny Hardaway, Charles Oakley, Mateen Cleaves. Tune in to get the inside scoop on what's happening in sports today.

  • Deepak Chopra Radio provides an online forum for compelling and thought provoking conversations on success, love, sexuality and relationships, well-being and spirituality.

  • Hits Radio covers basketball, sports culture and entertainment with past guests including Jason Kidd, Robin Lundberg and Chris Herren.

  • Listeners get an earful on The Halli Casser-Jayne Show, Talk Radio for Fine Minds. Whether it?s the current political cocktail or the latest must-read award-winning book, Halli tackles all topics and likes to stir ? and sometimes shakes ? things up.

  • Official Internet radio show of forthcoming epic paranormal investigation book by Eric Olsen and "Haunted Housewife" Theresa Argie.

  • Award-winning World Footprints is a leading voice in socially responsible travel and lifestyle. Hosts Ian & Tonya celebrate culture and heritage and bring a unique voice to the world of travel.

  • Football Reporters Online is a group of veteran football experts in the fields of coaching, scouting, talent evaluation, and writing/broadcasting/media placement. Combined, the group brings well over 100 years of expertise in sports.

  • Host John Martin interviews the nation's leading entrepreneurs and small biz experts to educate small business owners on how to be successful. Past guests have included Emeril Lagasse and Guy Kawasaki.

  • The Movie Geeks share their passion for the art through interviews with the stars of and creative minds behind your favorite flicks and pay tribute to big-screen legends. From James Cameron and Francis Ford Coppola to Ellen Burstyn and Robert Duvall, The Geeks have got'em all.

  • Sylvia Global presents global conversations pertaining to women, wealth, business, faith and philanthropy. Sylvia has interviewed an eclectic mix from CEOs and musicians to fashion designers and philanthropists including Randolph Duke and Ne-Yo.

  • Mr. Media host Bob Andelman goes one-on-one with the hottest, most influential minds from the worlds of film, TV, music, comedy, journalism and literature. That means A-listers like Kirk Douglas, Christian Slater, Kathy Ireland, Rick Fox, Chris Hansen and Jackie Collins.

  • Paula Begoun, best-selling author of Don't Go to the Cosmetics Counter Without Me, separates fact from fiction on achieving a radiant, youthful complexion at any age. She?s regularly joined by health and beauty experts who offer the latest on keeping your skin in tip-top shape.

  • Source: http://www.blogtalkradio.com/onegamingcommunity/2013/02/26/xbox-anonymous

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    Activists: Dozens killed in latest Syria fighting

    Displaced Syrian children play with cleaning tools in the Azaz camp for displaced people, north of Aleppo province, Syria, Thursday, Feb. 21, 2013. According to Syrian activists the number of people in the Azaz camp has grown by 3,000 in the last weeks due to heavier shelling by government forces. (AP Photo/Manu Brabo)

    Displaced Syrian children play with cleaning tools in the Azaz camp for displaced people, north of Aleppo province, Syria, Thursday, Feb. 21, 2013. According to Syrian activists the number of people in the Azaz camp has grown by 3,000 in the last weeks due to heavier shelling by government forces. (AP Photo/Manu Brabo)

    This citizen journalism image provided by Aleppo Media Center AMC which has been authenticated based on its contents and other AP reporting, shows an unexploded rocket from a Syrian warplane, in the neighborhood of Karam Alqasir, near Aleppo International Airport, in Aleppo, Syria, Thursday, Feb. 21, 2013. A car bomb near the Damascus headquarters of Syria's ruling party killed scores on Thursday, while a government airstrike on a rebel field hospital in southern Daraa left several dead, opposition activists and state media reported. (AP Photo/Aleppo Media Center AMC)

    BEIRUT (AP) ? Anti-regime activists say dozens of rebels and government forces have been killed in fighting near a police academy near the northern city of Aleppo.

    The Britain-based Syrian Observatory for Human Rights said Tuesday that the dead in the last two days of clashes included at least 26 rebel fighters, 40 soldiers and five pro-government militiamen.

    The activist group says the two sides have been shelling each other while the government has launched airstrikes.

    The police academy lies on the eastern side of Aleppo, Syria's largest city, which rebels have been battling to control since last July.

    The U.N. say some 70,000 have been killed since Syria's conflict began in March 2011.

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-02-26-Syria/id-ca80d5150e8843c6812c57279bbe4492

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    The Surprising Truth About Baby Boomer Health | Care2 Healthy ...

    From Woodstock, to women?s rights, Baby boomers have made a name for themselves by being unpredictable, off-beat pioneers; rejecting society?s norms and labels.

    But this time, the label they?re rejecting?that of the ?healthiest generation??may, in the long run, do them more harm than good.

    In spite of having access to groundbreaking medical advancements and record amounts of wealth, the baby boom generation is sicker and more impaired than their parents were at the same age, according to a new article published in the Journal of the American Medical Association.

    Baby boomer life expectancy does exceed that of previous generations, but their overall health is not better, study authors noted.

    And they know it too.

    Only 13 percent of baby boomers feel that their overall wellness is, ?excellent,? compared to 32 percent of people in the prior generation who gave their health top marks.

    Here are a few specific findings from the report:

    The positives: Baby boomers are less likely to smoke or have already had a heart attack than their parents were.

    The negatives: Baby boomers are much less likely to exercise on a regular basis?a whopping 52 percent said they get no regular physical activity. Consequently, they are also much more likely to be obese (39 percent of boomers versus 29 percent of the previous generation), have high cholesterol (74 percent versus 34 percent), and suffer from diabetes (16 percent versus 12 percent), than their parents.

    When they were their age, about nine percent of baby boomer parents had problems carrying out daily tasks, such as getting around the house and doing chores. Thirteen percent of boomers report currently having similar problems.

    Seven percent of boomers have to use a cane (or similar device) to get around, versus three percent of their parents at the same age.

    Make an action plan for healthy aging

    Aging baby boomers, even those who don?t feel in tip-top shape, shouldn?t view aging as a life-sentence of inevitable decline. There are steps you can take to help yourself age successfully.

    ?You may not be able to regain the health that you had at age 20 or 30, but you can always improve your physical and mental health,? says Larry Matson, Ed.D., co-author of the book, ?Live Young, Think Young, Be Young?at Any Age.?

    He suggests taking small, manageable steps to regain control over the common issues of aging that affect your physical and mental health.

    Set a goal to go for a 15 minute walk each day. Replace your daily diet soda with a glass of water, or all-natural juice. Eat a piece of fruit in place of dessert. Pay attention to and manage your stress levels by making an action plan to calm yourself down.

    ?The power of a different mindset about aging is the key,? Matson says. ?Raise your expectations and take it day by day. We?re all going to die, eventually, but even small changes can result in positive adaptations?no matter how old you are.?

    Discover more tips on how to incorporate better health habits into your daily routine:

    Baby Boomers Blaze New Trail as ?Unhealthiest? Generation originally appeared on AgingCare.com.

    Source: http://www.care2.com/greenliving/the-surprising-truth-about-baby-boomer-health.html

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    Looks like Pluto will have a moon named 'Vulcan'

    The votes are in for the SETI Institute's Pluto Rocks Poll, and, thanks in part to William Shatner, Mr. Spock's home planet is a clear winner.?

    By Jason Major,?Universe Today / February 25, 2013

    This photo provided and annotated by NASA/Hubble Space Telescope shows the five moons in their orbits around Pluto. The smallest moons ? no more than 20 miles (32 kilometers) across ? were discovered in that past two years and are currently referred to as P4 and P5.

    NASA/Hubble Space Telescope/AP

    Enlarge

    The votes have been tallied and the results are in from the SETI Institute?s?Pluto Rocks Poll: ?Vulcan? and ?Cerberus? have come out on top for names for Pluto?s most recently-discovered moons, P4 and P5.

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    After 450,324 votes cast over the past two weeks, Vulcan is the clear winner with a landslide 174,062 votes? due in no small part to a little?Twitter intervention by Mr. William Shatner,?I?m sure.

    In other words??yes,?the Trekkies have won.

    During a Google+ Hangout today,?SETI Institute?senior scientist Mark Showalter ? who discovered the moons and opened up the poll ? talked with SETI astronomer Franck Marchis and MSNBC?s Alan Boyle about the voting results. Showalter admitted that he wasn?t quite sure how well the whole internet poll thing would work out, but he?s pleased with the results.

    ?I had no idea what to expect,? said Showalter. ?As we all know the internet can be an unruly place? but by and large this process has gone very smoothly. I feel the results are fair.?

    As far as having a name from the Star Trek universe be used for an actual astronomical object?

    ?Vulcan works,? Showalter said. ?He?s got a family tie to the whole story. Pluto and Zeus were brothers, and Vulcan is a son of Pluto.?

    And what can you say when even?Mr. Spock agrees?

    The other winning name, Cerberus, is currently used for an asteroid. So because the IAU typically tries to avoid confusion with two objects sharing the same exact name, Showalter said he will use the Greek version of the spelling: Kerberos.

    The next step will be to submit these names to the International Astronomical Union for official approval, a process that could take 1?2 months.

    (Although who knows? maybe Bill can help move that process along as well?)

    Read more about the names on the Pluto Rocks ballot?here.

    Jason Major is a graphic artist from?Rhode Island?now living and working in?Dallas, Texas. He writes about astronomy and space exploration on his blog?Lights In The Dark, on Universe Today and also on?Discovery?News.

    This story originally appeared in?Universe Today.

    Want to stay on top of all the space news? Follow?@universetoday?on?Twitter

    Source: http://rss.csmonitor.com/~r/feeds/science/~3/5AH7txsgPWw/Looks-like-Pluto-will-have-a-moon-named-Vulcan

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    Toyota Celebrates 75 Years with Mind-Boggling Interactive Family ...

    Ad Age Events

    Join us April 16-17 for the best in digital innovation.
    Featuring: Delta, Starbucks, Amazon, Facebook, Google, Time Inc., Citibank, and more!

    Newsletters

    Big Data is more than web tracking and social media.
    Get the full scope of what?s happening in the evolving world of data and what it means to marketers.

    Source: http://adage.com/article/creativity-pick-of-the-day/toyota-celebrates-75-years-mind-boggling-interactive-family-tree/240042/

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    20 NYC schools starting Software Engineering Pilot program next year

    MAYOR BLOOMBERG AND SCHOOLS CHANCELLOR WALCOTT ANNOUNCE THE 20 SCHOOLS SELECTED FOR THE NEW SOFTWARE ENGINEERING PILOT PROGRAM

    Initiative to Expand Computer Science and Software Engineering Classes - First Announced in the State of the City - to Launch Next Fall

    Program to Help Prepare Students for College and Careers in Growing Tech Sector

    Mayor Michael R. Bloomberg and Schools Chancellor Dennis M. Walcott today announced the 20 schools selected for the new Software Engineering Pilot program to begin at the start of the next school year. The schools will receive comprehensive computer science and software engineering curriculum for the 1,000 students expected to participate this fall. By 2016, the program will grow to 3,500 students. Mayor Bloomberg first announced the Software Engineering Pilot in his State of the City address earlier this month, and the program is a part of the City's work to prepare students for college and careers in the technology sector. The Mayor and Chancellor Walcott made the announcement at the High School of Telecommunication Arts and Technology in Brooklyn, one of the 20 schools selected for the Software Engineering Pilot, and were joined by Deputy Mayor for Economic Development Robert K. Steel, AppNexus Cofounder and Chief Technology Officer Mike Nolet and Principal Philip Weinberg.

    "We know it's vital to prepare our children to succeed in an increasingly technology-centered economy and the Software Engineering Pilot will help us do just that," said Mayor Bloomberg. "This groundbreaking program will ensure that more students receive computer science and software engineering instruction so that they can compete for the tech jobs that are increasingly becoming a part of our city's economy. We're creating the home-grown workforce our city needs and teaching our students skills that will open up new doors for them and their future."

    "The tech industry in New York City continues to expand significantly under Mayor Bloomberg's leadership, and our public schools are rising to meet the challenge," said Chancellor Walcott. "The Software Engineering Pilot will provide students with the foundational skills they need to compete for high-paying, career track jobs in a variety of professional fields. I would like to thank the educators at our 20 pilot schools who are working hard to make this wonderful opportunity a reality for their students."

    "The Software Engineering Pilot is the latest component of our comprehensive strategy to position New York City to outperform in the knowledge economy of the future," said Deputy Mayor Steel. "From our work with the tech industry, we know that these companies need skilled employees at every level of their organization. The training we're providing through this program, the Academy for Software Engineering in Manhattan and the Applied Sciences NYC initiative will prepare our students for the jobs of today and tomorrow."

    "Hiring programmers and engineers is one of the biggest challenges facing AppNexus today and is critical to our success and growth," said Mike Nolet, Cofounder and Chief Technology Officer. "We applaud Mayor Bloomberg's leadership in preparing students for the jobs of the future. These students will surely benefit from learning computer science, and we will be hiring them as soon as possible!"

    "New York's future will be defined by the steps we take today to shape our diverse students into the programmers, engineers and designers that will fill 21st century tech jobs of tomorrow," said Reshma Saujani, founder of the nonprofit Girls Who Code. "The SEP Program is an innovative step forward in making that future brighter, and Girls Who Code is excited to partner with them to close the skills gap to give more minorities and young women opportunities they are currently being denied."

    "Giving students an opportunity for a bright future is the goal of every educator, and opportunity is what students will get when exposed to rigorous and engaging computer science education," said Cameron Wilson, Director of Public Policy for the Association for Computing Machinery. "The question we face is whether students will have access to this critical discipline because far too often they do not. New York City's Software Engineering Pilot's strategy to expand student access to high-quality computer science curriculum coupled with professional development for teachers, will give students knowledge and skills they can use to create new computing technologies and exposure to a field driving high-demand, high-paying jobs across numerous industries."

    In September, the Software Engineering Pilot will launch in 20 middle and high schools, bringing computer science and software engineering classes to students in grades 6 through 12. In the first year, the core topics to be taught include computer programming, embedded electronics, web design and programming, e-textiles, robotics and mobile computing. The Pilot will also offer elective classes, including digital fabrication, 3-D printing and animation.

    The 20 schools were selected through a competitive application process that evaluated the schools' current technology offerings and how the program could help grow and sustain the programming. They include:

    High School of Telecommunication Arts and Technology
    Brooklyn Technical High School
    The Bronx Compass High School
    The Renaissance Charter High School for Innovation
    Urban Assembly Gateway School for Technology
    Queens Vocational & Technical High School
    Cambria Heights Academy
    Ralph McKee High School
    New Dorp High School
    Ditmas Intermediate School 62
    I.S. 30 Mary White Ovington
    Mark Twain I.S. 239 for the Gifted and Talented
    Bronx Park Middle School
    M.S. 223 The Laboratory School of Finance and Technology
    Tompkins Square Middle School
    Nathaniel Hawthorne Middle School 74
    J.H.S. 185 Edward Bleeker
    Pathways College Preparatory School
    J.H.S. 157 Stephen A. Halsey
    Eagle Academy for Young Men
    The Software Engineering Pilot will also provide teacher training for the instructors leading the classes. Schools will use rigorous academic curriculum and have access to technology resources to support program instruction. Participating high schools will also receive support in applying for New York State Education Department approval, which can award a Career and Technical Education endorsement to graduating students who complete the program.

    The Software Engineering Pilot aligns to Common Core Learning Standards by developing students' higher order thinking skills through the incorporation of industry-informed learning experiences. By emphasizing the analysis of complex text and mathematical modeling, participating students will extend their preparation in English Language Arts & Literacy and Mathematics while leveraging cutting-edge technology and curricula to develop the academic and personal behaviors that are a benchmark of college and career readiness.

    The program also builds on the Applied Sciences NYC initiative that the Bloomberg Administration launched to capitalize on the considerable growth in the city's science, technology and research fields. In the technology sector, employment in New York grew by nearly 30 percent between 2005 and 2010, with total employment now at nearly 120,000. The City has established three partnerships expected to create more than 48,000 jobs and 1,000 new companies and will be led by: Cornell and the Technion, which is developing a campus on Roosevelt Island; the NYU-led consortium, which will build the Center for Urban Science and Progress in Downtown Brooklyn; and Columbia University, which will establish the new Institute for Data Sciences and Engineering, to be located at Columbia's Morningside Heights and Washington Heights campuses.

    Source: http://www.engadget.com/2013/02/26/nyc-school-software/

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    Tuesday, February 26, 2013

    Dennis Rodman worms his way into North Korea

    PYONGYANG, North Korea (AP) ? Former NBA star Dennis Rodman brought his basketball skills Tuesday and flamboyant style ? neon-bleached hair, tattoos, nose studs and all ? to the isolated communist country with possibly the world's drabbest dress code: North Korea.

    Arriving in Pyongyang, the American athlete and showman known as "The Worm" became an unlikely ambassador for sports diplomacy at a time of heightened tensions between the U.S. and North Korea. Or maybe not so unlikely: Young leader Kim Jong Un is said to have been a fan of the Chicago Bulls in the 1990s, when Rodman won three championships with the club.

    Rodman is joining three members of the Harlem Globetrotters basketball team for a Vice Media production to air on HBO in early April, Vice founder Shane Smith told The Associated Press in an exclusive interview before the group's departure from Beijing.

    Smith said the Americans hope to engage in a little "basketball diplomacy" by running a basketball camp for children and playing pickup games with locals, and by competing alongside top athletes of North Korea ? formally known as the Democratic People's Republic of Korea.

    "Is sending the Harlem Globetrotters and Dennis Rodman to the DPRK strange? In a word, yes," said Smith, who is host of the upcoming series. "But finding common ground on the basketball court is a beautiful thing."

    Rodman might seem an odd fit for an impoverished country where male fashion rarely ventures beyond military khaki and growing facial hair is forbidden. During his heyday in the 1990s, Rodman was a poster boy for excess. He called his 1996 autobiography "Bad as I Wanna Be" ? and showed up wearing a wedding dress to promote it.

    Shown a photo of a snarling Rodman, piercings dangling from his lower lip and two massive tattoos emblazoned on his chest, one North Korean in Pyongyang recoiled and said: "He looks like a monster!"

    But Rodman is also a Hall of Fame basketball player and one of the best defenders and rebounders to ever play the game. During a storied, often controversial career, he won five NBA championships ? a feat that quickly overshadowed his antics for at least one small North Korean group of basketball fans.

    Rodman's is the second high-profile American visit this year to North Korea, a country that remains in a state of war with the U.S. It also comes two weeks after North Korea conducted an underground nuclear test in defiance of U.N. bans against atomic and missile activity.

    Google's executive chairman, Eric Schmidt, made a surprise four-day trip to Pyongyang, where he met with officials and toured computer labs in January, just weeks after North Korea launched a satellite into space on the back of a long-range rocket.

    Washington, Tokyo, Seoul and others consider both the rocket launch and the nuclear test provocative acts that threaten regional security.

    North Korea characterizes the satellite launch as a peaceful bid to explore space, but says the nuclear test was meant as a deliberate warning to Washington. Pyongyang says it needs to build nuclear weapons to defend itself against the U.S., and is believed to be trying to build an atomic bomb small enough to mount on a missile capable of reaching the mainland U.S.

    Vice, known for its sometimes irreverent journalism, has made two previous visits to North Korea, coming out with the "VICE Guide to North Korea." The HBO series, which will air weekly starting April 5, features documentary-style news reports from around the world.

    The Americans also will visit North Korea's national monuments, the SEK animation studio and a new skate park in Pyongyang.

    The U.S. State Department hasn't been contacted about travel to North Korea by this group, a senior administration official said, requesting anonymity to comment before any trip had been made public. The official said the department does not vet U.S. citizens' private travel to North Korea and urges U.S. citizens contemplating travel there to review a travel warning on its website.

    In a now-defunct U.S.-North Korean agreement in which Washington had planned last year to give food aid to Pyongyang in exchange for nuclear concessions, Washington had said it was prepared to increase people-to-people exchanges with the North, including in the areas of culture, education and sports.

    Promoting technology and sports are two major policy priorities of Kim Jong Un, who took power in December 2011 following the death of his father, Kim Jong Il.

    Along with soccer, basketball is enormously popular in North Korea, where it's not uncommon to see basketball hoops set up in hotel parking lots or in schoolyards. It's a game that doesn't require much equipment or upkeep.

    The U.S. remains Enemy No. 1 in North Korea, and North Koreans have limited exposure to American pop culture. But they know Michael Jordan, a former teammate of Rodman's when they both played for the Chicago Bulls in the 1990s.

    During a historic visit to North Korea in 2000, then-Secretary of State Madeleine Albright presented Kim Jong Il, famously an NBA fan, with a basketball signed by Jordan that later went on display in the huge cave at Mount Myohyang that holds gifts to the leaders.

    North Korea even had its own Jordan wannabe: Ri Myong Hun, a 7-foot-9 star player who is said to have renamed himself "Michael" after his favorite player and moved to Canada for a few years in the 1990s in hopes of making it into the NBA.

    Even today, Jordan remains well-loved here. At the Mansudae Art Studio, which produces the country's top art, a portrait of Jordan spotted last week, complete with a replica of his signature and "NBA" painted in one corner, seemed an odd inclusion among the propaganda posters and celadon vases on display.

    An informal poll of North Koreans revealed that "The Worm" isn't quite as much a household name in Pyongyang.

    But Kim Jong Un was a basketball-crazy adolescent when Rodman, now 51, was with the Bulls, and when the Harlem Globetrotters, an exhibition basketball team, kept up a frenetic travel schedule worldwide.

    In a memoir about his decade serving as Kim Jong Il's personal sushi chef, a man who goes by the pen name Kenji Fujimoto recalled that basketball was the young Kim Jong Un's biggest passion, and that the Chicago Bulls were his favorite.

    The notoriously unpredictable and irrepressible Rodman said he has no special antics up his sleeve for making his mark on one of the world's most regimented and militarized societies, a place where order and conformity are enforced with Stalinist fervor.

    But he said he isn't leaving any of his piercings behind.

    __

    Associated Press writer Matthew Pennington contributed to this report from Washington. Follow AP's bureau chief for Pyongyang and Seoul at www.twitter.com/newsjean.

    Source: http://news.yahoo.com/dennis-rodman-worms-way-north-korea-051224872.html

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    Taking the gamble out of DNA sequencing: How much can be learned in a large-scale experiment

    Feb. 24, 2013 ? Two USC scientists have developed an algorithm that could help make DNA sequencing affordable enough for clinics -- and could be useful to researchers of all stripes.

    Andrew Smith, a computational biologist at the USC Dornsife College of Letters, Arts and Sciences, developed the algorithm along with USC graduate student Timothy Daley to help predict the value of sequencing more DNA, to be published in Nature Methods on February 24.

    Extracting information from the DNA means deciding how much to sequence: sequencing too little and you may not get the answers you are looking for, but sequence too much and you will waste both time and money. That expensive gamble is a big part of what keeps DNA sequencing out of the hands of clinicians. But not for long, according to Smith.

    "It seems likely that some clinical applications of DNA sequencing will become routine in the next five to 10 years," Smith said. "For example, diagnostic sequencing to understand the properties of a tumor will be much more effective if the right mathematical methods are in place."

    The beauty of Smith and Daley's algorithm, which predicts the size and composition of an unseen population based on a small sample, lies in its broad applicability.

    "This is one of those great instances where a specific challenge in our research led us to uncover a powerful algorithm that has surprisingly broad applications," Smith said.

    Think of it: how often do scientists need to predict what they haven't seen based on what they have? Public health officials could use the algorithm to estimate the population of HIV positive individuals; astronomers could use it to determine how many exoplanets exist in our galaxy based on the ones they have already discovered; and biologists could use it to estimate the diversity of antibodies in an individual.

    The mathematical underpinnings of the algorithm rely on a model of sampling from ecology known as capture-recapture. In this model, individuals are captured and tagged so that a recapture of the same individual will be known -- and the number of times each individual was captured can be used to make inferences about the population as a whole.

    In this way scientists can estimate, for example, the number of gorillas remaining in the wild. In DNA sequencing, the individuals are the various different genomic molecules in a sample. However, the mathematical models used for counting gorillas don't work on the scale of DNA sequencing.

    "The basic model has been known for decades, but the way it has been used makes it highly unstable in most applications. We took a different approach that depends on lots of computing power and seems to work best in large-scale applications like modern DNA sequencing," Daley said.

    Scientists faced a similar problem in the early days of the human genome sequencing project. A mathematical solution was provided by Michael Waterman of USC, in 1988, which found widespread use. Recent advances in sequencing technology, however, require thinking differently about the mathematical properties of DNA sequencing data.

    "Huge data sets required a novel approach. I'm very please it was developed here at USC," said Waterman.

    This research was funded by grants from the National Institutes of Health National Human Genome Research Institute (R01 HG005238 and P50 HG002790).

    Share this story on Facebook, Twitter, and Google:

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    Story Source:

    The above story is reprinted from materials provided by University of Southern California, via EurekAlert!, a service of AAAS.

    Note: Materials may be edited for content and length. For further information, please contact the source cited above.


    Journal Reference:

    1. Timothy Daley, Andrew D Smith. Predicting the molecular complexity of sequencing libraries. Nature Methods, 2013; DOI: 10.1038/nmeth.2375

    Note: If no author is given, the source is cited instead.

    Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/3-uOSnhnewE/130224142825.htm

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    8 Online Tools To Create A Professional, Slick Resume

    One of the most important things to get the attention of the employer is your CV/resume. This is because when you apply for a job anywhere in the world, the first thing that the employer sees is your resume and based on that, they decide whether to call you for an interview or not. It should include everything about you, your strengths, education and work experience, awards and certifications you have and your skills.

    It?s not just the skills and your education that catches attention. In order to attract the interest of your employer, you have to make sure that your resume is unique, simple and professionally designed. If you are looking for a simple yet easy way to design a professionally looking resume/CV, we have gathered a list of some handy online tools. Take a look.

    CV Maker

    CV Maker is an easy to use online utility that can help users create professional CVs online. The service provides users with 5 different templates to choose from. The best thing about the service is that you do not have to go through annoying registration procedure if you want to create your CV. All you have to do is visit CV Maker and create your CV right away. Unlike other services, it even takes seconds to create an account on CV Maker.

    CVMaker

    Registered users get the benefit of saving their CVs online so that they can edit it any time they want rather than creating it from scratch. To get started, CV Maker will display different sections of the CV which you can fill depending on your qualifications and work experience. You can even add any section which you think is not there like Awards or any other section. After creating your CV, you can preview it online or download it to your PC in 3 different formats: PDF, HTML and Text.

    Price: Free

    Resumonk

    Resumonk is yet another handy service that allows users to create resume online. The service has some decent templates to choose from and also offers premium templates. To get started, you must sign up for an account on Resumonk so that you can easily manage and create your CV online.

    Resumonk

    Using Resumonk is pretty simple and straight forward. All you have to do is follow the on screen instructions and add your information. After entering complete information, you can either download the CV as PDF or view it online. The service offers a pro plan as well that allows users to import their data from LinkedIn as well as access to premium templates.

    Price: Free | $9.99 One Time Payment for Premium Templates

    Free Resume Creator

    As the name suggests, Free Resume Creator allows users to create elegant resumes without signing up for any account or anything of that sort. What I really like about this service is that it offers users with over 20 beautiful resume templates to choose from.

    Free Resume Creator

    All you have to do is select the temple and input your information. After completing your CV, you have the option of downloading it to your computer in multiple formats including PDF, Word, HTML and Text, If you want, you can even sign up for an account so that you can save and manage your CV online. With Free Resume Creator, you cannot only create resumes but it also helps users create cover letters, business cards, reference pages, etc.

    Price: Free

    Revu

    Revu is something really different when it comes to resume creation. As the tagline of the service states ?Don?t send your resume. Share your story?. The service does exactly that by presenting your resume and work details in such a way that is different and eye catching.

    revu

    After signing up, the service creates your personalized URL which serves as your resume. After adding all the relevant details, you can share the profile URL with your employer which can be viewed on any device. You can even upload your traditional resume and it will add the link to it on your profile page which can be downloaded by any employer who wants to view it. You can even keep track of who has checked out your profile and how much time he/she spent on viewing it.

    Price: Free

    VisualCV

    Just like Revu, VisualCV offers users with a totally different way to create an attractive CV that can attract the attention of the employer. With VisualCV, you can attach videos, documents and other media elements in your CV.

    VisualCV

    Once registered, just fill in the required information just as you would do in any other resume creator. You can create a standard resume with VisualCV as well. The place where it beats resume creators is the fact that users can add elements such as presentations, documents, images, etc to their resume.

    Price: Free

    JobSpice

    Jobspice is another simple and easy to use online tool that allows users to create resumes. The service allows users to create resumes without signing up for any account or anything. All you have to do is enter the relevant fields and design your resume. The site offers free as well as premium templates that users can use.

    JobSpice

    After creating your resume, you can download your resume in PDF or docx format and share it with your employer.

    Price: Free | Premium Templates

    ResumeBaking

    ResumeBaking is another simple and easy to use tool to create professional resumes online. To create a resume, you must fill out all the sections on the ResumeBaking?s resume builder and you are done. If you want, you can even import your data from LinkedIn and Facebook as well. Unlike other services, ResumeBaking is not free and requires users to sign up for a paid account in order to view and download the resume.

    ResumeBaking

    That may be the downside of this service as majority of other services in the list offers the same features free of cost. The only reason why it may be worth the price I allows users to get messages from employers, create cover letters and most importantly search for jobs, view resume statistics and get notifications online. Apart from that, I would have recommended this service if it offered a free plan.

    Price: $1 per month/ $3.95 per month/ $8.95 per month

    Razume

    Last but not the least; Razume is yet another online service that allows users to create a professional CV in few minutes. After signing up, you will be asked to fill in the relevant details such as your education, work experience, extracurricular activities or simply anything you want to add to your CV. ?After creating, you can then download it to your PC as well.

    Razume

    Unlike other tools, the site does not offer many custom templates but the one it creates looks simple and elegant. One thing that makes it different from the other tools mentioned above is that it also asks users to tag their resumes. What it means is that it asks you to select the country, your field of expertise, your majors and your salary range. After creating your resume, it saves the resume for online employers who can then review your resume based on the tags you selected.

    Price: Free

    All the above tools are really simple and easy to use. I gave each and every tool in the list a try and in the end, I must say that when it comes to ease of use and traditional CV, CV Maker is the right tool for you as it allows users to add information without any trouble and offers elegant templates that can attract the attention of the employer. Resumonk is good as well compared to CV Maker but personally, I think the templates offered by CV Maker are far better than the free ones offered by Resumonk.

    On the other hand, if you really wish to make a CV that can stand out from the rest of the crowd, VisualCV is the tool you should use. The additional feature of adding media elements to your resume can be really helpful. Revu is also something unique but it might be very difficult for an amateur user to use and create a visually appealing CV.

    If you know about any other useful resume creation tool, we?d love to hear about them in the comments below!

    Image Credits: Recruiter

    Source: http://web.appstorm.net/roundups/data-management-roundups/8-online-tools-to-create-a-professional-slick-resume/

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    Doctor says Iraqi president speaking after stroke

    BAGHDAD (AP) ? Iraqi President Jalal Talabani is able to speak and understand people around him as he recovers from a stroke he suffered in December, a doctor responsible for his medical care said Sunday.

    In an interview, Dr. Najmaldin Karim described the improvement in the president's health as encouraging. Karim is a neurosurgeon who is also governor of the Iraqi province of Kirkuk. He oversees Talabani's medical care when he is in Iraq, although the president is currently in Germany for treatment.

    "He's improving. He's talking. He's conversing. He understands when he's spoken to. It's a good development," Karim said. "We're very encouraged and excited by this."

    Karim said he is in daily contact with Talabani's German medical team. He is hopeful Talabani will be able to return to Iraq, but acknowledged that any decision rests with the doctors treating him in Europe.

    "We'll have to just take it one day at a time," he said.

    The 79-year-old Talabani was rushed to a hospital late on Dec. 17 after suffering a stroke. Few specific details have been released about his health, fueling intense speculation about the seriousness of his condition and his ability to continue with his job. He was flown to a Berlin area hospital for further treatment shortly after his condition was stabilized.

    No images of Talabani have been released since he fell ill, and he has not been heard from personally.

    Some Iraqi officials and Baghdad-based diplomats have said he slipped into a coma shortly after the stroke happened, or was otherwise gravely incapacitated.

    Talabani is overweight and has undergone several medical procedures in recent years, including heart surgery in 2008 and knee replacement surgery last year.

    On Feb. 18, Talabani's office issued a statement saying the president continues to respond well to therapy. Two presidential officials reached Sunday declined to comment, saying that Karim is the only person authorized to discuss Talabani's condition.

    The Iraqi presidency is a largely ceremonial role, with the prime minister acting as the head of government. But Talabani is seen by many Iraqis as something of a unifying statesman, and he has at times played an important role in mediating disputes among the country's ethnic and sectarian factions.

    Talabani became ill at a particularly crucial moment in Iraqi politics. His stroke occurred while he was trying to calm an ongoing dispute between the central government and Iraq's Kurdish ethnic minority, from which he hails. Meanwhile, tens of thousands of Sunni Muslims have been rallying for nearly two months against the Shiite-led government, increasing sectarian tensions nearly a decade after the U.S.-led invasion.

    ___

    Follow Adam Schreck on Twitter at http://twitter.com/adamschreck

    Source: http://news.yahoo.com/doctor-says-iraqi-president-speaking-stroke-113932110.html

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    Listing Fail: Two Not-So-'Sparkling' Homes | AOL Real Estate


    Home with 'sparkling' pool

    Unless your home has Swarovski crystals studding its walls or dangling from glass chandeliers in every room, we'd strongly suggest against calling it "sparkling." Still, it's a descriptor that's used frequently, albeit erroneously, in many listings and it annoys us as much as "stunning" and "cavernous."

    Take, for example, this listing in Phoenix (pictured above). We have two issues with this home, which has, as described, a "sparkling POOL!" One, just because it's filled with water does not mean it is "sparkling." Two, even if the pool were sparkling like a diamond earring, you wouldn't even notice thanks to the dirty, unfinished backyard surrounding it! (Though we will say that, relative to the home's unpleasing backyard, the pool appears somewhat luminous -- as would anything.)

    Then there's this listing in Louisville, Ky. (pictured above). The listing describes a "sparkling home" with "fresh paint." While we don't doubt the home is freshly painted, unless the paint is infused with glitter or reflective properties, we don't see how this home "sparkles" in the least.

    Thanks to our pals at Curbed for the tips!

    Enjoy this post? Check out all our listing fail articles!

    More on AOL Real Estate:
    Find out how to
    calculate mortgage payments.
    Find
    homes for sale in your area.
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    foreclosures in your area.
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    Follow us on Twitter at @AOLRealEstate or connect with AOL Real Estate on Facebook.

    Source: http://realestate.aol.com/blog/2013/02/25/listing-fail-two-not-so-sparkling-homes/

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    South Africa win the 3-match series 3-0... Who is to be blamed in the Pakistani...

    Sorry, Readability was unable to parse this page for content.

    Source: http://www.facebook.com/Emirates247/posts/494839480553779

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    Monday, February 25, 2013

    'Fox News Sunday' to interview Mitt and Ann Romney (Washington Post)

    Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS and RSS Feed via Feedzilla.

    Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/287079148?client_source=feed&format=rss

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    Mad Catz F.R.E.Q. 7 gaming headset hands-on

    Mad Catz announced the F.R.E.Q. 7 gaming headset last week, and the company has the $200 cans on hand here at Mobile World Congress. As you may recall, the marquee spec is Dolby Pro Logic IIx processing, which expands 5.1-channel audio to 7.1 channels for a richer aural experience. Another cool feature: these over-ears come bundled with both a standard stereo connector and a cord with USB for connecting directly to your computer (both have mini-USB on one end). The F.R.E.Q. 7 wasn't plugged in so we can't speak to sound quality, but they feel lightweight, and the red color really pops in real life. (There's also a matte black option.) The devices are currently available for pre-order, but you can get a hands-on look now in our gallery.

    Mad Catz F.R.E.Q. 7 gaming headset hands-on

    Zach Honig contributed to this report.

    Source: http://www.engadget.com/2013/02/24/mad-catz-f-r-e-q-7-gaming-headset-hands-on/

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    Scientists find genes linked to human neurological disorders in sea lamprey genome

    Feb. 24, 2013 ? Scientists at the Marine Biological Laboratory (MBL) have identified several genes linked to human neurological disorders, including Alzheimer's disease, Parkinson's disease and spinal cord injury, in the sea lamprey, a vertebrate fish whose whole-genome sequence is reported this week in the journal Nature Genetics.

    "This means that we can use the sea lamprey as a powerful model to drive forward our molecular understanding of human neurodegenerative disease and neurological disorders," says Jennifer Morgan of the MBL's Eugene Bell Center for Regenerative Biology and Tissue Engineering. The ultimate goals are to determine what goes wrong with neurons after injury and during disease, and to determine how to correct these deficits in order to restore normal nervous system functions.

    Unlike humans, the lamprey has an extraordinary capacity to regenerate its nervous system. If a lamprey's spinal cord is severed, it can regenerate the damaged nerve cells and be swimming again in 10-12 weeks.

    Morgan and her collaborators at MBL, Ona Bloom and Joseph Buxbaum, have been studying the lamprey's recovery from spinal cord injury since 2009. The lamprey has large, identified neurons in its brain and spinal cord, making it an excellent model to study regeneration at the single cell-level. Now, the lamprey's genomic information gives them a whole new "toolkit" for understanding its regenerative mechanisms, and for comparing aspects of its physiology, such as inflammation response, to that of humans.

    The lamprey genome project was accomplished by a consortium of 59 researchers led by Weiming Li of Michigan State University and Jeramiah Smith of the University of Kentucky. The MBL scientists' contribution focused on neural aspects of the genome, including one of the project's most intriguing findings.

    Lampreys, in contrast to humans, don't have myelin, an insulating sheath around neurons that allows faster conduction of nerve impulses. Yet the consortium found genes expressed in the lamprey that are normally expressed in myelin. In humans, myelin-associated molecules inhibit nerves from regenerating if damaged. "A lot of the focus of the spinal cord injury field is on neutralizing those inhibitory molecules," Morgan says.

    "So there is an interesting conundrum," Morgan says. "What are these myelin-associated genes doing in an animal that doesn't have myelin, and yet is good at regeneration? It opens up a new and interesting set of questions, " she says. Addressing them could bring insight to why humans lost the capacity for neural regeneration long ago, and how this might be restored.

    At present, Morgan and her collaborators are focused on analyzing which genes are expressed and when, after spinal cord injury and regeneration. The whole-genome sequence gives them an invaluable reference for their work.

    Morgan, Bloom, and Buxbaum collaborate at the MBL through funding by the Charles Evans Foundation. Bloom is based at the Feinstein Institute for Medical Research/Hofstra North Shore-Long Island Jewish in New York. Buxbaum is from Mount Sinai School of Medicine in New York.

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    Story Source:

    The above story is reprinted from materials provided by Marine Biological Laboratory, via EurekAlert!, a service of AAAS.

    Note: Materials may be edited for content and length. For further information, please contact the source cited above.


    Journal Reference:

    1. Jeramiah J Smith, Shigehiro Kuraku, Carson Holt, Tatjana Sauka-Spengler, Ning Jiang, Michael S Campbell, Mark D Yandell, Tereza Manousaki, Axel Meyer, Ona E Bloom, Jennifer R Morgan, Joseph D Buxbaum, Ravi Sachidanandam, Carrie Sims, Alexander S Garruss, Malcolm Cook, Robb Krumlauf, Leanne M Wiedemann, Stacia A Sower, Wayne A Decatur, Jeffrey A Hall, Chris T Amemiya, Nil R Saha, Katherine M Buckley, Jonathan P Rast, Sabyasachi Das, Masayuki Hirano, Nathanael McCurley, Peng Guo, Nicolas Rohner, Clifford J Tabin, Paul Piccinelli, Greg Elgar, Magali Ruffier, Bronwen L Aken, Stephen M J Searle, Matthieu Muffato, Miguel Pignatelli, Javier Herrero, Matthew Jones, C Titus Brown, Yu-Wen Chung-Davidson, Kaben G Nanlohy, Scot V Libants, Chu-Yin Yeh, David W McCauley, James A Langeland, Zeev Pancer, Bernd Fritzsch, Pieter J de Jong, Baoli Zhu, Lucinda L Fulton, Brenda Theising, Paul Flicek, Marianne E Bronner, Wesley C Warren, Sandra W Clifton, Richard K Wilson, Weiming Li. Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution. Nature Genetics, 2013; DOI: 10.1038/ng.2568

    Note: If no author is given, the source is cited instead.

    Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/31_IzH_8VG8/130224142915.htm

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